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Agonists and Antagonists

Agonist: An agonist is a drug that stimulates certain brain receptors.
Full agonist opioids completely activate the opioid receptors in the brain, producing the full opioid impact.
Antagonists: Antagonist is the opposite of agonist. An antagonist is a drug that binds to the receptor either at the main location or at another site, preventing the receptor from responding. Antagonist is the polar opposite of agonist. Opioid antagonists prevent opioids from acting in the brain.

Full and partial agonists:

  1. Alfentanil

  2. Buprenorphine

  3. Butorphanol

  4. Codeine

  5. Diphenoxylate

  6. Fentanyl

  7. Heroin

  8. Hydrocodone

  9. Hydromorphone

  10. Levorphanol

  11. Loperamide

  12. Meperidine

  13. Methadone

  14. Morphine

  15. Opium

  16. Oxycodone

  17. Oxymorphone

  18. Pentazocine

  19. Remifentanil

  20. Sufentanil

  21. Tramadol

Opiate antagonists:

  1. Naldemedine

  2. Nalmefene

  3. Naloxegol

  4. Naloxone

  5. Naltrexone


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